Dose Schedule and Antitumor Studies of Arabinosyl Cytosine ( NSC 6387 S ) 6 7 Writing
نویسندگان
چکیده
The University of Oklahoma Medical Center, Oklahoma City, Oklahoma The University of Texas Medical Branch, Galveston, Texas ^he University of Texas M. D. Anderson Hospital and Tumor Institute, Houston, Texas The University of Texas Southwestern Medical School, Dallas, Texas Tulane University School of Medicine, New Orleans, Louisiana University of Arkansas Medical Center, Little Rock, Arkansas University of Virginia School of Medicine, Charlottesville, Vir ginia Washington University School of Medicine, St. Louis, Missouri Wilford Hall USAF Hospital, Lackland Air Force Base, Texas
منابع مشابه
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We evaluated the interaction of a biochemically active concentration of cyclopentenyl cytosine (CPE-C), an investigational antimetabolite which inhibits CTP synthetase, on the cytotoxicity of arabinosyl-5-azacytosine (Ara-AC) and 1-beta-D-arabinofuranosylcytosine (Ara-C) in HCT 116 colon carcinoma cells. A 3-h exposure to 0.5 microM CPE-C depleted CTP pools by over 90% and decreased dCTP pools ...
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تاریخ انتشار 2006